diff --git a/src/toolkit/actors/PictureInPictureChild-sys-mjs.patch b/src/toolkit/actors/PictureInPictureChild-sys-mjs.patch
new file mode 100644
index 000000000..dc39ee311
--- /dev/null
+++ b/src/toolkit/actors/PictureInPictureChild-sys-mjs.patch
@@ -0,0 +1,12 @@
+diff --git a/toolkit/actors/PictureInPictureChild.sys.mjs b/toolkit/actors/PictureInPictureChild.sys.mjs
+index 7ae1aa58bbaeab7a1835a3ea8328735d4f4ecfb1..9d0679dde3c031c2459c09ffbc157f32bc7d003a 100644
+--- a/toolkit/actors/PictureInPictureChild.sys.mjs
++++ b/toolkit/actors/PictureInPictureChild.sys.mjs
+@@ -291,6 +291,7 @@ export class PictureInPictureLauncherChild extends JSWindowActorChild {
+       if (
+         video &&
+         PictureInPictureChild.videoIsPlaying(video) &&
++        !video.muted &&
+         PictureInPictureChild.videoIsPiPEligible(video)
+       ) {
+         this.togglePictureInPicture({ video, reason: "AutoPip" }, false);